Patent ductus arteriosus is associated with acute kidney injury in the preterm infant.

Batoule MajedDavid A BatemanNatalie UyFangming Lin

Published in: Pediatric nephrology (Berlin, Germany) (2019)

Moderate-to-large PDA was strongly associated with all stages of AKI in preterm infants ≤ 28 weeks of gestational age. Effective NSAID treatment decreased the risk of severe but not mild AKI. These differential effects reflect the balance between the renal benefits of PDA closure and the risk of NSAID toxicity.

Keyphrases

gestational age
preterm infants
birth weight
preterm birth
acute kidney injury
low birth weight
oxidative stress
high intensity
early onset
body mass index
replacement therapy
weight gain