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Altered methylation of imprinted genes in neuroblastoma: implications for prognostic refinement.

Medha SumanMaja LöfgrenSusanne FranssonJewahri Idris YousufJohanna SvenssonAnna DjosTommy MartinssonPer KognerTeresia KlingHelena Carén
Published in: Journal of translational medicine (2024)
Aberrant methylation in imprinted regions is frequently occurring in NB tumours and several of these regions have independent prognostic value. Thus, these could serve as potentially important clinical epigenetic markers to identify individuals with adverse prognosis. Incorporation of methylation status of these regions together with the established risk predictors may further refine the prognostication of NB patients.
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