Familial coaggregation of major psychiatric disorders among first-degree relatives of patients with obsessive-compulsive disorder: a nationwide study.
Mao-Hsuan HuangChih-Ming ChengShih-Jen TsaiYa-Mei BaiCheng-Ta LiWei-Chen LinTung-Ping SuTzeng-Ji ChenMu-Hong ChenPublished in: Psychological medicine (2020)
The FDRs, including parents, offspring, siblings, and twins, of patients with OCD have a higher risk of OCD, schizophrenia, bipolar disorder, MDD, ADHD, and ASD. The familial co-aggregation of OCD with OCD and other major psychiatric disorders was existent in a dose-dependent manner. Given the increased risks of psychiatric disorders, medical practitioners should closely monitor the mental health of the FDRs of patients with OCD.
Keyphrases
- obsessive compulsive disorder
- bipolar disorder
- deep brain stimulation
- major depressive disorder
- mental health
- autism spectrum disorder
- attention deficit hyperactivity disorder
- healthcare
- early onset
- primary care
- intellectual disability
- working memory
- type diabetes
- metabolic syndrome
- risk assessment
- adipose tissue
- general practice
- insulin resistance