Neuroactive Steroid (3α,5α)3-hydroxypregnan-20-one (3α,5α-THP) and Pro-inflammatory Cytokine MCP-1 Levels in Hippocampus CA1 are Correlated with Voluntary Ethanol Consumption in Cynomolgus Monkey.

Matthew C BeattieChristopher S ReguyalPatrizia PorcuJames B DaunaisKathleen A GrantA Leslie Morrow

Published in: Alcoholism, clinical and experimental research (2017)

These data indicate that voluntary, long-term EtOH consumption results in higher levels of 3α,5α-THP, while decreasing levels of MCP-1 in the CA1 hippocampus, and that both changes may be linked to HPA axis function and the magnitude of voluntary EtOH consumption.

Keyphrases

machine learning
protein kinase
big data
prefrontal cortex
deep learning
artificial intelligence
data analysis