AGEs promote atherosclerosis by increasing LDL transcytosis across endothelial cells via RAGE/NF-κB/Caveolin-1 pathway.
Meng ShuWenzhuo ChengXiong JiaXiangli BaiYing ZhaoYajing LuLin ZhuYan ZhuLi WangYan ShuYi SongSi JinPublished in: Molecular medicine (Cambridge, Mass.) (2023)
AGEs accelerate the development of diabetes-related AS by increasing the LDL transcytosis in ECs through the activation of the RAGE/NF-κB/Caveolin-1 axis, which may be targeted to prevent or treat diabetic macrovascular complications.
Keyphrases