Detection of polyreactive immunoglobulin G facilitates diagnosis in children with autoimmune hepatitis.
Bastian EngelJana DiestelhorstKatharina Luise Hupa-BreierTheresa KirchnerNicole HenjesStephanie LogesMuhammed YukselWojciech JanczykClaudine LalanneKalliopi ZachouYe H OoJérôme GournaySimon PapeJoost P H DrenthAmédée RenandGeorge N DalekosLuigi MuratoriPiotr SochaYun MaCigdem ArikanUlrich BaumannMichael P MannsHeiner WedemeyerNorman JungeElmar JaeckelRichard TaubertPublished in: Hepatology international (2024)
Detecting pIgG improves the diagnostic evaluation of pediatric AIH compared to conventional autoantibodies, primarily owing to higher accuracy and specificity.