Survival prediction algorithms for COVID-19 patients admitted to a UK district general hospital.
Ancy FernandezNonyelum ObiechinaJustin KohAnna HongAngela NandiTimothy M ReynoldsPublished in: International journal of clinical practice (2021)
Data, including outcome data (discharged alive/died), were extracted for 487 consecutive patients, admitted for treatment. Overall, patients who died were older, had very significantly lower Oxygen saturation (SpO2) on admission, required a higher inspired Oxygen concentration (IpO2) and higher CRP as evidenced by a Bonferroni-corrected (P < 0.0056). Evaluated individually, platelets and lymphocyte count were not statistically significant but when used in a logistic regression to develop a predictive score, platelet count did add predictive value. The 5-parameter prediction algorithm we developed was: [Formula: see text] CONCLUSION: Age, IpO2 on admission, CRP, platelets and number of lungs consolidated were effective marker combinations that helped identify patients who would be likely to survive. The AUC under the ROC Plot was 0.8129 (95% confidence interval 0.0.773 - 0.853; P < .001).
Keyphrases
- machine learning
- peripheral blood
- emergency department
- electronic health record
- big data
- deep learning
- coronavirus disease
- sars cov
- healthcare
- physical activity
- south africa
- artificial intelligence
- middle aged
- community dwelling
- smoking cessation
- data analysis
- red blood cell
- free survival
- preterm infants
- adverse drug
- human milk
- acute care
- preterm birth