Renal-Limited Antiglomerular Basement Membrane Disease Related To Alemtuzumab: A Case Report.
Amye M HarriganMichael L WestLaurette GeldenhuysPenelope S PoyahPublished in: Canadian journal of kidney health and disease (2020)
Anti-GBM disease is a life-altering adverse event that can be associated with alemtuzumab. Our case highlights the limitations of monitoring urinalyses as a trigger for anti-GBM antibody testing in patients who have received alemtuzumab and have baseline abnormal urinalyses; such patients may require further protocolized anti-GBM antibody testing, although the optimal frequency of such antibody screening remains unclear.