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Targeting the Gut Microbiota of Vertically HIV-Infected Children to Decrease Inflammation and Immunoactivation: A Pilot Clinical Trial.

Talia SainzLaura DiazDavid RojoMaría Isabel ClementeCoral BarbasMaría José GosalbesNuria Jimenez-HernandezLuis EscosaSara GuillenJosé Tomás RamosMaria Angeles Muñoz-FernándezMaría Luisa NavarroMaría José MelladoSergio Serrano-Villar
Published in: Nutrients (2022)
In this exploratory study, a four-week nutritional supplementation had no significant effects in terms of decreasing inflammation, microbial translocation, or T-cell activation in HIV-infected children. However, the correlations found support the interaction between gut microbiota and the immune system.
Keyphrases
  • hiv infected
  • antiretroviral therapy
  • clinical trial
  • oxidative stress
  • young adults
  • human immunodeficiency virus
  • study protocol
  • microbial community
  • open label
  • drug delivery
  • phase ii
  • double blind