Login / Signup

Rh-relaxin-2 attenuates degranulation of mast cells by inhibiting NF-κB through PI3K-AKT/TNFAIP3 pathway in an experimental germinal matrix hemorrhage rat model.

Peng LiGang ZhaoFanfan ChenYan DingTianyi WangShengpeng LiuWeitian LuWeilin XuJerry FloresUmut OcakTongyu ZhangJohn H ZhangJi-Ping Tang
Published in: Journal of neuroinflammation (2020)
Our findings showed that rh-relaxin-2 attenuated degranulation of mast cells and neuroinflammation, improved neurological outcomes, and ameliorated hydrocephalus after GMH through RXFP1/PI3K-AKT/TNFAIP3/NF-κB signaling pathway.
Keyphrases