Monoacylglycerol Lipase Inhibition Protects From Liver Injury in Mouse Models of Sclerosing Cholangitis.

Matteo TardelliFrancesca Virginia BruschiClaudia D FuchsThierry ClaudelNicole AuerVictoria KunczerMaximilian BaumgartnerOnne A H O RondaHenk Jan VerkadeTatjana StojakovicHubert ScharnaglAida HabibRobert ZimmermannSophie LotersztajnMichael Trauner

Published in: Hepatology (Baltimore, Md.) (2019)

Collectively, our study unravels MGL as a metabolic target, demonstrating that MGL inhibition may be considered as potential therapy for sclerosing cholangitis.

Keyphrases

liver injury
drug induced
mouse model
human health