Mesenchymal stromal cells for ocular surface repair.
Olla Al-JaibajiStephen SwiokloChe J ConnonPublished in: Expert opinion on biological therapy (2019)
Depending on the environmental cues, MSCs can exert a potent effect on corneal wound healing through reducing opacity and vascularization, whilst promoting re-epithelialization. Whilst their mechanism is multifactorial, it seems clear that the anti-inflammatory/immunomodulatory factors they produce in response to damage are key to their control of cellular milieu and improving healing outcomes.