How we approach thrombosis risk in children with COVID-19 infection and MIS-C.
Anjali A SharathkumarE Vincent S FaustinoClifford M TakemotoPublished in: Pediatric blood & cancer (2021)
Thrombosis within the microvasculature and medium to large vessels is a serious and common complication among critically ill individuals with coronavirus disease 2019 (COVID-19). While children are markedly less likely to develop severe disease than adults, they remain at risk for thrombosis during acute infection and with the post-acute inflammatory illness termed multisystem inflammatory syndrome in children. Significant knowledge deficits in understanding COVID-19-associated coagulopathy and thrombotic risk pose clinical challenges for pediatric providers who must incorporate expert opinion and personal experience to manage individual patients. We discuss clinical scenarios to provide framework for characterizing thrombosis risk and thromboprophylaxis in children with COVID-19.
Keyphrases
- coronavirus disease
- pulmonary embolism
- sars cov
- young adults
- liver failure
- healthcare
- end stage renal disease
- oxidative stress
- traumatic brain injury
- respiratory syndrome coronavirus
- newly diagnosed
- drug induced
- venous thromboembolism
- ejection fraction
- intensive care unit
- respiratory failure
- chronic kidney disease
- patient reported outcomes
- aortic dissection
- prognostic factors
- extracorporeal membrane oxygenation
- case report
- acute respiratory distress syndrome
- breast cancer risk