Definition and validation of the Design Space for co-milled nasal powder containing nanosized lamotrigine.
P GieszingerIoan TomuţăT CasianCs BartosPiroska Szabó-RévészR AmbrusPublished in: Drug development and industrial pharmacy (2018)
From the DS generated by the software, an optimal formulation was obtained and the results validated the experimental design. The QbD approach was a useful and effective tool of understanding the parameters that affect the quality of the desired product.