Loss of ARID1A Promotes Hepatocellular Carcinoma Progression via Up-regulation of MYC Transcription.

Yao XiaoGuodong LiuXiwu OuyangDenggao ZaiJixiang ZhouXiaoli LiQi ZhangJie Zhao

Published in: Journal of clinical and translational hepatology (2021)

These results describe ARID1A as a tumor suppressor in the liver. A deficiency in ARID1A predicts worse survival in HCC patients and promotes HCC progression via up-regulation of MYC transcription.

Keyphrases

transcription factor
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
patient reported outcomes
patient reported