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Neurite Orientation Dispersion and Density Imaging (NODDI) of Brain Microstructure in Adolescent Cannabis and Nicotine Use.

Alexander L WallaceKelly Elizabeth CourtneyNatasha E WadeLaura E HatzRachel BacaAaron JacobsonThomas T LiuJoanna Jacobus
Published in: Behavioral sciences (Basel, Switzerland) (2024)
NTP use was associated with altered white matter integrity in an adolescent and young adult sample. Findings suggest that NTP-associated alterations may be linked to altered fiber tract geometry and dispersed neurite structures versus myelination, as well as differential effects of NTP and cannabis use on white matter structure. Future work is needed to investigate how altered white matter is related to downstream behavioral effects from NTP use.
Keyphrases
  • white matter
  • young adults
  • multiple sclerosis
  • high resolution
  • mental health
  • childhood cancer