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A pilot study to determine the effects of nasal co-phenylcaine on drug-induced sleep endoscopy.

Alfonso Luca PendolinoIvor KwameAnne-Lise PoirrierMaral J RouhaniSamit UnadkatGiuliana PretiGiancarlo OttavianoPeter J AndrewsBhik Kotecha
Published in: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery (2019)
Our pilot study supports the use of co-phenylcaine nasal spray during DISE and the positive effects of the nasal spray do not influence the grading outcome. Importantly, the decongestant enhances the nasal assessment during DISE and potentially aids in the diagnosis of nasal obstruction while the nasal anaesthetic component may be beneficial by reducing nasal discomfort during DISE and thereby helping to reduce the total dose of intravenous anaesthetic administered. However, further studies on a larger population are needed to confirm our results.
Keyphrases
  • chronic rhinosinusitis
  • drug induced
  • liver injury
  • high dose
  • antiretroviral therapy