Midline Low-Grade Gliomas of Early Childhood: Focus on Targeted Therapies.
Ludmila PapushaMargarita ZaytsevaAgnesa PanferovaEkaterina SalnikovaAlexey SamarinIrina VilesovaKirill VoroninAnastasia ProtsvetkinaSvetlana PodlipaevaIlya ZakharovNatalia UsmanEugene I HwangAlexander KarachunskiyRoger J PackerGalina A NovichkovaAlexander E DruyPublished in: JCO precision oncology (2024)
mLGGs of early childhood are often aggressive tumors, resistant to CT, and frequently require alternative treatment. The majority of patients harbor druggable molecular targets and respond to molecular TT.
Keyphrases
- low grade
- high grade
- end stage renal disease
- newly diagnosed
- chronic kidney disease
- ejection fraction
- computed tomography
- prognostic factors
- single molecule
- magnetic resonance
- image quality
- magnetic resonance imaging
- positron emission tomography
- contrast enhanced
- patient reported outcomes
- dual energy
- combination therapy