Macrophage-Derived Exosomes in TLR9 -/- Mice Ameliorate Sepsis-Induced Mitochondrial Oxidative Stress and Apoptosis in Cardiomyocytes.
Xiang LiJunyu LuoYanmei LiLu JiaYuejin LiShili YeLanlan LiuYanxuan YuYonggang LuYun-Peng LuanPublished in: Oxidative medicine and cellular longevity (2022)
in macrophages suppressed the inflammatory reaction as well as the exosome secretion and resulted in the inhibition of apoptosis and oxidative stress in sepsis-induced cardiomyopathy.
Keyphrases
- oxidative stress
- diabetic rats
- high glucose
- dna damage
- ischemia reperfusion injury
- induced apoptosis
- intensive care unit
- acute kidney injury
- septic shock
- heart failure
- adipose tissue
- toll like receptor
- cell death
- endoplasmic reticulum stress
- type diabetes
- heat shock
- stem cells
- drug induced
- endothelial cells
- nuclear factor
- high fat diet induced
- insulin resistance
- wild type