Whole blood transcriptional profiles as a prognostic tool in complete and incomplete Kawasaki Disease.

Preeti JaggiAsuncion MejiasZhaohui XuHan YinMelissa Moore-ClingenpeelBennett SmithJane C BurnsAdriana H TremouletAlejandro Jordan-VillegasDamien ChaussabelKaren TexterVirginia PascualOctavio Ramilo

Published in: PloS one (2018)

A reproducible biosignature from KD patients was identified, and was similar in children with cKD and inKD. A genomic score allowed early identification of children at higher risk for non-response to IVIG.

Keyphrases

end stage renal disease
chronic kidney disease
young adults
ejection fraction
newly diagnosed
gene expression
peritoneal dialysis
prognostic factors
transcription factor
copy number
dna methylation
heat stress