Celastrol mitigates inflammation in sepsis by inhibiting the PKM2-dependent Warburg effect.
Piao LuoQian ZhangTian-Yu ZhongJia-Yun ChenJun-Zhe ZhangYa TianLiu-Hai ZhengFan YangLing-Yun DaiChang ZouZhi-Jie LiJing-Hua LiuJi-Gang WangPublished in: Military Medical Research (2022)
Cel inhibits inflammation and the Warburg effect in sepsis via targeting PKM2 and HMGB1 protein.