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Celastrol mitigates inflammation in sepsis by inhibiting the PKM2-dependent Warburg effect.

Piao LuoQian ZhangTian-Yu ZhongJia-Yun ChenJun-Zhe ZhangYa TianLiu-Hai ZhengFan YangLing-Yun DaiChang ZouZhi-Jie LiJing-Hua LiuJi-Gang Wang
Published in: Military Medical Research (2022)
Cel inhibits inflammation and the Warburg effect in sepsis via targeting PKM2 and HMGB1 protein.
Keyphrases
  • oxidative stress
  • intensive care unit
  • acute kidney injury
  • septic shock
  • radiation therapy
  • amino acid
  • protein protein