Clinical Outcome and Prognostic Factors of Pancreatic Adenosquamous Carcinoma Compared to Ductal Adenocarcinoma-Results from the German Cancer Registry Group.
Rüdiger BraunMonika Klinkhammer-SchalkeSylke Ruth ZeissigKees Kleihus van TolLouisa BolmKim Christin HonselmannEkaterina PetrovaHryhoriy LapshynSteffen DeichmannThaer S A AbdallaBenjamin HeckelmannPeter BronsertSergii ZemskovRichard HummelTobias KeckUlrich Friedrich WellnerPublished in: Cancers (2022)
In conclusion, ASCP showed poorer differentiation and higher frequency of blood vessel invasion indicative of a more aggressive tumor biology. ASCP was a significant prognostic factor for overall survival in a multivariable analysis. Overall survival of resected ASCP patients was significantly shorter compared to resected PDAC patients. However, surgical resection still improved survival significantly.