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Naldemedine is associated with earlier defecation in critically ill patients with opioid-induced constipation: A retrospective, single-center cohort study.

Seiya NishiyamaShigehiko UchinoYusuke SasabuchiTomoyuki MasuyamaAlan Kawarai LeforMasamitsu Sanui
Published in: PloS one (2024)
The present study shows that naldemedine is associated with earlier defecation in critically ill patients with opioid-induced constipation.
Keyphrases
  • high glucose
  • chronic pain
  • pain management
  • drug induced
  • irritable bowel syndrome
  • endothelial cells
  • oxidative stress