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Modeling the Interplay between HDV and HBV in Chronic HDV/HBV Patients.

Adequate MhlangaRami ZakhAlexander ChurkinVladimir ReinharzJeffrey S GlennOhad EtzionScott J CotlerCihan YurdaydinDanny BarashHarel Dahari
Published in: Mathematics (Basel, Switzerland) (2022)
Hepatitis D virus is an infectious subviral agent that can only propagate in people infected with hepatitis B virus. In this study, we modified and further developed a recent model for early hepatitis D virus and hepatitis B virus kinetics to better reproduce hepatitis D virus and hepatitis B virus kinetics measured in infected patients during anti-hepatitis D virus treatment. The analytical solutions were provided to highlight the new features of the modified model. The improved model offered significantly better prospects for modeling hepatitis D virus and hepatitis B virus interactions.
Keyphrases
  • hepatitis b virus
  • liver failure
  • ejection fraction
  • newly diagnosed
  • mass spectrometry
  • combination therapy
  • smoking cessation