OptPipe - a pipeline for optimizing metabolic engineering targets.
András HartmannAna Vila-SantaNicolai KallscheuerMichael VogtAlice Julien-LaferrièreMarie-France SagotJan MarienhagenSusana VingaPublished in: BMC systems biology (2017)
A method was developed to combine the optimization solutions provided by common knockout prediction procedures and rank the suggested mutants according to the expected growth rate, production and a new adaptability measure. The implementation of the pipeline along with the complete documentation is freely available at https://github.com/AndrasHartmann/OptPipe .