Exosomal lncRNA CHL1-AS1 Derived from Peritoneal Macrophages Promotes the Progression of Endometriosis via the miR-610/MDM2 Axis.

Ting LiuMei LiuCaihua ZhengDaoyan ZhangMingbao LiLu Zhang

Published in: International journal of nanomedicine (2021)

The results demonstrate that exosomal lncRNA CHL1-AS1 promotes the proliferation, migration, and invasion of eESCs and inhibits their apoptosis by downregulating miR-610 and upregulating MDM2, which might be a potential therapeutic target for EMs.

Keyphrases

long non coding rna
long noncoding rna
cell proliferation
oxidative stress
signaling pathway
cell death
cell cycle arrest
pi k akt