Diagnostic value of cardiovascular magnetic resonance in comparison to endomyocardial biopsy in cardiac amyloidosis: a multi-centre study.

Grigorios ChatzantonisMichael BietenbeckAhmed ElsanhouryCarsten TschöpeBurkert PieskeGloria TauscherJulia VietheerZornitsa ShomanovaHeiko MahrholdtAndreas RolfSebastian KelleAli Yilmaz

Published in: Clinical research in cardiology : official journal of the German Cardiac Society (2020)

Non-invasive CMR shows an excellent diagnostic accuracy and yield regarding CA. When combined with monoclonal protein studies, CMR can differentiate ATTR from AL with high accuracy and predictive value. However, invasive EMB remains a safe invasive gold-standard and allows to differentiate CA from other cardiomyopathies that can also cause LV hypertrophy.

Keyphrases

magnetic resonance
multiple myeloma
left ventricular
protein kinase
computed tomography
protein protein
binding protein
small molecule
atrial fibrillation