Immunotheranostic target modules for imaging and navigation of UniCAR T-cells to strike FAP-expressing cells and the tumor microenvironment.
Liliana R LoureiroLydia HoffmannChristin NeuberLuise RuppClaudia ArndtAlexandra KeglerManja KubeilChristoph E HagemeyerHolger StephanMarc SchmitzAnja FeldmannMichael Philipp BachmannPublished in: Journal of experimental & clinical cancer research : CR (2023)
These findings demonstrate that the novel αFAP TMs are promising immunotheranostic tools to foster cancer imaging and treatment, paving the way for a more convenient, individualized, and safer treatment of cancer patients.