Genetically proxied antidiabetic drugs targets and stroke risk.

Yahui ZhuMao LiHongfen WangFei YangXinyuan PangRongrong DuJinghong ZhangXu-Sheng Huang

Published in: Journal of translational medicine (2023)

Our findings showed that genetic proxies for sulfonylureas targets by lowering blood glucose were associated with a lower risk of any stroke and any ischemic stroke. The study might be of great significance to guide the selection of glucose-lowering drugs in individuals at high risk of stroke.

Keyphrases

blood glucose
atrial fibrillation
glycemic control
blood pressure
genome wide
metabolic syndrome
gene expression
dna methylation
adipose tissue
brain injury