Intraoperative renal hypoxia and risk of cardiac surgery-associated acute kidney injury.
Jennifer P NgoKhin M NoeMichael Z L ZhuAndrew MartinMeg OllasonAndrew D CochraneJuliann A SmithAmanda G ThriftRoger G EvansPublished in: Journal of cardiac surgery (2021)
Intraoperative change in pEPO does not predict AKI. However, UPO2 shows promise, particularly in patients with higher risk of operative mortality. The disparity between these two markers of renal hypoxia may indicate that UPO2 reflects medullary oxygenation whereas pEPO reflects cortical oxygenation.