Investigating the prognostic ability of health-related quality of life on survival: a prospective cohort study of adults with lung cancer.

This is the first study to compare the prognostic ability of pre-diagnosis, post-diagnosis, and HRQOL changes for OS. The prognostic value of HRQOL at distinct points in the cancer continuum underscores the importance of routine HRQOL monitoring as part of patient-centered cancer care.