A patient-centered composite endpoint weighting technique for orthopaedic trauma research.

Ugochukwu N UdogwuAndrea HoweKatherine FreyMarckenley IsaacDaniel ConnellyDimitrius MarinosMitchell BakerRenan C CastilloGerard P SlobogeanRobert V O'TooleRobert V O'Toole

Published in: BMC medical research methodology (2019)

This study revealed that patients' relative importance towards clinical outcomes followed a logical gradient, with distinct and quantifiable preferences for each possible component outcome. These findings were incorporated into a novel composite endpoint weighting technique.

Keyphrases

end stage renal disease
newly diagnosed
chronic kidney disease
peritoneal dialysis
single cell
patient reported