Herpes simplex virus-2 transmission following solid organ transplantation: Donor-derived infection and transplantation from prior organ recipients.
Nenad MacesicIain J AbbottMatthew KayeJulian DruceAllan R GlanvillePaul J GowPeter D HughesTony M KormanWilliam R MulleyPhillip J O'ConnellHelen OpdamMiranda ParaskevaMatthew C PitmanStella SetyapranataWilliam D RawlinsonPaul D R JohnsonPublished in: Transplant infectious disease : an official journal of the Transplantation Society (2017)
Donor-derived HSV infection affected two clusters of recipients because of transplantation of organs from a prior organ recipient. HSV should be considered as a possible cause of illness in febrile SOT recipients in the immediate post-transplant period and may cause disseminated disease and re-infection in HSV-2-seropositive recipients. Testing of HSV serology and prophylaxis may be considered in SOT recipients not receiving cytomegalovirus prophylaxis.