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Comparison of genome-wide gene expression profiling by RNA Sequencing versus microarray in bronchial biopsies of COPD patients before and after inhaled corticosteroid treatment: does it provide new insights?

Benedikt DitzJeunard G BoekhoudtHananeh AlieeFabian J TheisMartijn C NawijnCorry-Anke BrandsmaPieter S HiemstraHidde J HaismaGaik W TewMichele A GrimbaldestonMargaret NeighborsVictor GuryevMaarten van den BergeAlen Faiz
Published in: ERJ open research (2021)
More DEGs are detected by RNA-Seq than microarrays in COPD lung biopsies and are associated with immunological pathways. Performing bulk tissue cell-type deconvolution in microarray lung samples, using the SVR method, reflects RNA-Seq results. https://bit.ly/2N8sY3s.
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