The impact of obesity and endocrine therapy on the prognosis of premenopausal women with hormone receptor-positive breast cancer: A single-institute retrospective study.
Yukinori OzakiJun MasudaAkemi KataokaTakahiro KogawaTomomi AbeHidetomo MorizonoLina InagakiFumikata HaraToshimi TakanoTakayuki UenoShinji OhnoPublished in: Cancer reports (Hoboken, N.J.) (2022)
High BMI was associated with worse prognosis in premenopausal patients with HR-positive BC who received adjuvant TAM. The role of OFS as adjuvant endocrine therapy remains unclear, and further studies are required to explore the adequate management of obese premenopausal patients.
Keyphrases
- positive breast cancer
- postmenopausal women
- end stage renal disease
- metabolic syndrome
- early stage
- weight loss
- type diabetes
- newly diagnosed
- adipose tissue
- insulin resistance
- chronic kidney disease
- weight gain
- body mass index
- prognostic factors
- peritoneal dialysis
- stem cells
- breast cancer risk
- bariatric surgery
- obese patients
- mesenchymal stem cells
- high fat diet induced