Dynamic changes in insulin and glucagon during disease progression in rhesus monkeys with obesity-related type 2 diabetes mellitus.

Can WangYao XiaoJue WangNing HouWeiyi CuiXiaomin HuFanxin ZengYe YuanDongwei MaXueting SunYan ZhangWen ZhengYuli LiuHaibao ShangLiangyi ChenRui-Ping XiaoXiuqin Zhang

Published in: Diabetes, obesity & metabolism (2019)

Our findings showed that, beside the decreased insulin level, hyperglucagonaemia also plays an important role in the development of T2DM.

Keyphrases

glycemic control
type diabetes
weight loss
insulin resistance
metabolic syndrome
cardiovascular disease
skeletal muscle
physical activity
body mass index
cardiovascular risk factors