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Liquid-based cytology features of pancreatic acinar cell carcinoma: comparison with other non-ductal neoplasms of the pancreas.

Minji KwonSeung-Mo HongKyoungbun LeeHaeryoung Kim
Published in: Journal of pathology and translational medicine (2024)
ACC had characteristic cytological features that could be observed on LBC preparations, such as high cellularity, necrotic/apoptotic background, nuclear tangles, acinar arrangement of cells, and macronucleoli. These findings also help distinguish ACC from PanNEN and SPN on LBC. It is important to be familiar with these features, as an accurate diagnosis on endoscopic ultrasound-guided fine needle aspiration cytology would have impact on the management of the patient.
Keyphrases
  • fine needle aspiration
  • ultrasound guided
  • induced apoptosis
  • cell death
  • cell cycle arrest
  • high resolution
  • mass spectrometry
  • endoplasmic reticulum stress