Defining COMMD4 as an anti-cancer therapeutic target and prognostic factor in non-small cell lung cancer.

Amila SuraweeraAlex DuffMark N AdamsChristian JekimovsPascal H G DuijfCheng LiuMatthew McTaggartSam BeardKenneth J O'ByrneDerek J Richard

Published in: British journal of cancer (2020)

Our data indicate that COMMD4 may function as a prognostic factor in ADC NSCLC. Additionally, COMMD4 is a potential therapeutic target for NSCLC, as its depletion induces cancer cell death.

Keyphrases

prognostic factors
cell death
small cell lung cancer
advanced non small cell lung cancer
papillary thyroid
brain metastases
electronic health record
big data
diffusion weighted imaging
cell cycle arrest
diffusion weighted
squamous cell carcinoma
young adults
childhood cancer
signaling pathway
machine learning