Disorder of sex development with germ cell tumors: Which is uncovered first?
Cecile Faure ConterDaniel OrbachBrice FresneauCécile VeritéJacinthe BonneauEstelle ThebaudMaryline PoiréeSandrine ThouveninClaire PluchartPierre Yves MureFrederique DijoudYves MorelPublished in: Pediatric blood & cancer (2020)
DSD are often uncovered at the time of GCT diagnosis (11/16 cases). This should prompt oncologists to rule out a DSD in patients with GCT, even in case of pubertal development. Earlier recognition of Klinefelter syndrome could potentially lead to GCT detection at an earlier stage.