Disorder of sex development with germ cell tumors: Which is uncovered first?

Cecile Faure Conter Daniel Orbach Brice FresneauCécile VeritéJacinthe BonneauEstelle ThebaudMaryline PoiréeSandrine ThouveninClaire PluchartPierre Yves MureFrederique DijoudYves Morel

Published in: Pediatric blood & cancer (2020)

DSD are often uncovered at the time of GCT diagnosis (11/16 cases). This should prompt oncologists to rule out a DSD in patients with GCT, even in case of pubertal development. Earlier recognition of Klinefelter syndrome could potentially lead to GCT detection at an earlier stage.

Keyphrases

germ cell
loop mediated isothermal amplification
palliative care
quantum dots