Suppression of obesity by melatonin through increasing energy expenditure and accelerating lipolysis in mice fed a high-fat diet.

Tsuguhito OtaDandan LiHaoran LiOuyang ZhangYaxin HuangHengrong ShaoYajiao WangSuili CaiYuqin ZhuShengnan Jin Chunming Ding

Published in: Nutrition & diabetes (2022)

Melatonin suppressed obesity and insulin resistance resulting from the HFD by enhancing BAT activity and energy expenditure, and these effects were dependent on FGF21.

Keyphrases

insulin resistance
high fat diet
high fat diet induced
adipose tissue
metabolic syndrome
skeletal muscle
polycystic ovary syndrome
type diabetes
weight loss
body mass index