Risk factors for progression of chronic kidney disease: An investigation in prepubertal children.
Gertruida van BiljonCornelius J MeintjesPiet J BekkerVictor O L KarusseitPublished in: Nephrology (Carlton, Vic.) (2023)
Common modifiable risk factors, when present at initial evaluation, were not independently associated with CKD progression to kidney failure in prepubertal children. Only non-modifiable risk factors and proteinuria predicted eventual stage 5 disease. The physiological changes of puberty may be the major precipitator of kidney failure during adolescence.