Signatures of malignant cells and novel therapeutic targets revealed by single-cell sequencing in lung adenocarcinoma.

Jiaqi LiangZhencong ChenYiwei HuangGuoshu BiYunyi BianXing JinHuan ZhangQihai SuiCheng Zhan Qun Wang

Published in: Cancer medicine (2022)

Our model can aid the analyses of single-cell sequencing data. CAPN8, IRX2, and SPINK13 may serve as novel targets of targeted and immune-based therapies in lung adenocarcinoma.

Keyphrases

single cell
rna seq
induced apoptosis
high throughput
cell cycle arrest
electronic health record
big data
cancer therapy
endoplasmic reticulum stress
gene expression
machine learning
dna methylation
data analysis