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Distribution and Molecular Characterization of Resistance Gene Cassettes Containing Class 1 Integrons in Multi-Drug Resistant (MDR) Clinical Isolates of Pseudomonas aeruginosa.

Leila AhmadianMohammad Reza HaghshenasBahman MirzaeiZahra Norouzi BazgirHamid Reza Goli
Published in: Infection and drug resistance (2020)
The treatment of infections caused by P. aeruginosa in this region of Iran is a major problem due to the high prevalence of class 1 integrons. It seems that the high prescription of beta-lactams and aminoglycosides for the treatment of these infections may be replaced by other combination therapy stewardships.
Keyphrases
  • combination therapy
  • drug resistant
  • multidrug resistant
  • pseudomonas aeruginosa
  • acinetobacter baumannii
  • cystic fibrosis
  • copy number
  • staphylococcus aureus
  • dna methylation
  • transcription factor