Clearing soluble MIC reverses the impaired function of natural killer cells from patients with multiple myeloma.

Sojeong KimHaerim ChungJeong-Eun KwakYu Ri KimChung Hyun ParkYeonhee KimJune-Won CheongJennifer WuEui-Cheol Shin Hyunsoo ChoJin Seok Kim

Published in: Journal for immunotherapy of cancer (2024)

Our findings indicate targeting soluble MIC with huB10G5 might be a viable therapeutic approach to promote NKG2D-dependent cellular immunotherapy outcome in MM.

Keyphrases

multiple myeloma
nk cells
cancer therapy
network analysis
natural killer cells