Involvement of chronic inflammation via monocyte chemoattractant protein-1 in uraemic cardiomyopathy: a human biopsy study.

Tomoya Nakano Kenji OnoueAyako SenoSatomi IshiharaYasuki NakadaHitoshi NakagawaTomoya UedaTaku Nishida Tsunenari SoedaMakoto WatanabeRika KawakamiKinta HatyakeyamaYasuhiro SakaguchiChiho Ohbayashi Yoshihiko Saito

Published in: ESC heart failure (2021)

These results suggest that activated PlGF/Flt-1 signalling and subsequent macrophage-mediated chronic non-infectious inflammation via MCP-1 in the myocardium are involved in the pathogenesis of UCM.

Keyphrases

endothelial cells
oxidative stress
acute myeloid leukemia
heart failure
dendritic cells
tyrosine kinase
ultrasound guided
protein protein
induced pluripotent stem cells
small molecule
immune response
amino acid
peripheral blood
atrial fibrillation