Abortion induces reactivation of inflammation in relapsing-remitting multiple sclerosis.
Doriana LandiPaolo RagoneseLuca ProsperiniViviana NocitiShalom HaggiagAntonio CorteseRoberta FantozziSimona PontecorvoElisabetta FerraroMaria Chiara BuscarinuGiorgia MataluniFabrizia MonteleoneMarco SalvettiGiancarlo Di BattistaAda FranciaEnrico MillefioriniClaudio GasperiniMassimiliano MirabellaGiuseppe SalemiLaura BoffaCarlo PozzilliDiego CentonzeGirolama Alessandra MarfiaPublished in: Journal of neurology, neurosurgery, and psychiatry (2018)
Abortion was associated with clinical and radiological inflammatory rebound remarkably in the first 12 months postevent. Deregulated proinflammatory processes arising at the early stages of pregnancy might play a role both in MS reactivation and abortion. Women with MS should be counselled about these risks of abortion and followed up accordingly.