Duration of replication-competent SARS-CoV-2 shedding among patients with severe or critical coronavirus disease 2019 (COVID-19).

Do Young KimMichael Y LinCheryl JenningsHaiying LiJae Hyung JungNicholas M MooreIsaac GhinaiStephanie R BlackDaniel J ZaccaroJohn BrofmanMary K Haydennull null

Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2022)

Immunocompromise and persistent or recurrent symptoms were associated with shedding of replication-competent SARS-CoV-2, supporting the need for improving respiratory symptoms in addition to time as criteria for discontinuation of transmission-based precautions. Our results suggest that the period of potential infectiousness among immunocompetent patients with severe or critical COVID-19 may be similar to that reported for patients with milder disease.

Keyphrases

sars cov
coronavirus disease
respiratory syndrome coronavirus
early onset
sleep quality
human health
climate change