Comparison of clot waveform analysis with or without adjustment between prothrombin time and activated partial thromboplastin time assays to assess in vitro effects of direct oral anticoagulants.

Masatoshi WakuiYuta FujimoriYuko OzakiShusaku OkaMaria ZiparoEmiri OsadaYoshino KondoTerumichi NakagawaShoko NakamuraHiromichi Matsushita

Published in: Clinica chimica acta; international journal of clinical chemistry (2024)

The results revealed distinct features of DOAC effects in extrinsic and intrinsic pathways. To ascertain the clinical implication, further studies using clinical samples are needed.

Keyphrases

direct oral anticoagulants
venous thromboembolism
atrial fibrillation
single cell
high throughput
case control