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A new nucleosomic-based model to identify and diagnose SSc-ILD.

Julien GuiotMonique HenketBéatrice AndreMarielle HerzogNathalie HardatMakon-Sebastien NjockCatherine MoermansMichel MalaiseRenaud Louis
Published in: Clinical epigenetics (2020)
In our study, we identified a new blood-based model with nucleosomic biomarker in order to diagnose SSc-ILD in a SSc cohort. This model is correlated with TLC and FVC at baseline and predictive of the skin evolution and the DLCO. Further longitudinal exploration studies should be performed in order to evaluate the potential of such diagnostic and predictive model.
Keyphrases
  • interstitial lung disease
  • rheumatoid arthritis
  • risk assessment
  • human health