18F-FDG PET/CT Findings in Cytomegalovirus Colitis.
Anna Sophie L KjaerIben RibberholtKim ThomsenPer H IbsenElena MarkovaJesper GraffPublished in: Diagnostics (Basel, Switzerland) (2018)
We present a case demonstrating the diagnostic work-up of a patient undergoing azathioprine treatment for inflammatory bowel disease (IBD), diagnosed with an acute cytomegalovirus (CMV) infection and CMV colitis. An 18F-FDG positron emission tomography/computed tomography (PET/CT) performed 2 weeks after debut of symptoms revealed pathological 18F-FDG uptake in the left side of the colon mucosa, mimicked activity of IBD. However, a diagnosis of CMV colitis was based on the presence of CMV IgM antibodies, a seroconversion of CMV IgG antibodies, presence of CMV DNA in plasma and the finding af CMV DNA in biopsies from the intestinal mucosa. The patient responded to treatment with ganciclovir. This case highlights that a positive 18F-FDG PET/CT scan of the colon can be due to CMV colitis.
Keyphrases
- positron emission tomography
- computed tomography
- pet ct
- ulcerative colitis
- pet imaging
- epstein barr virus
- case report
- magnetic resonance imaging
- atrial fibrillation
- intensive care unit
- single molecule
- cell free
- depressive symptoms
- single cell
- physical activity
- acute respiratory distress syndrome
- respiratory failure
- replacement therapy
- extracorporeal membrane oxygenation
- aortic dissection